COUCHES MINCES PROTÉIQUES MULTICOUCHES, PROCÉDÉS DE PRODUCTION, DISPOSITIFS DE DISTRIBUTION DE MÉDICAMENT ET IMPLANTS BIOMÉDICAUX UTILISANT LESDITES COUCHES MINCES
VIKINGE, ELLA CATHRINE,ENGSTRÖM, ELIN,ARONSSON, HENRIK,AXELSSON, OSKAR
申请号：
EP10780883
公开号：
EP2435102A4
申请日:
2010.05.24
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
A multilayer protein film has a mass of greater than 0.5 μg/cm2 and consists essentially of protein. A drug delivery device comprises the multilayer protein film onto which a pharmaceutically active agent can be loaded. A biomedical implant comprises an implant substrate and the multilayer protein film on at least a portion of the implant substrate surface. A method of making a multilayer protein film having a mass of greater than 0.5 μg/cm2 comprises contacting a substrate with a protein solution at a temperature of from about 30° C. to about 95° C, wherein a multilayer protein film having a mass of greater than 0.5 μg/cm2 is formed on the substrate.
