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ALPHA-DERIVATIVES OF CIS-MONOUNSATURATED FATTY ACIDS, INTENDED FOR USE AS A MEDICINE
专利权人:
УНИВЕРСИТАТ ДЕ ЛЕЗ ИЛЬ БАЛЕАР (ES)
发明人:
ЭСКРИБА РУИС Пабло Висенте (ES),БУСКЕТС КСАУБЕТ Ксавьер (ES),БАРСЕЛО КОБЛИХН Гвендолин (ES),ЛЬАДО КАНЬЕЛЬАС Виктория (ES),АЛЬВАРЕС МАРТИНЕС Рафаэль (ES),ТЕРЕС ХИМЕНЕС Сильвия (ES),ЛОПЕС Даниэль (ES),Б
申请号:
RU2011128335/04
公开号:
RU2011128335A
申请日:
2009.12.04
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. The compound of Formula I: -COO-CH- (CH) -CH = CH- (CH) -CH, its salts and its pharmaceutically acceptable derivatives, where they can take any value from 0 to 14, can be substituted by any atom or group of atoms with an atomic / molecular weight of 4 to 200 Yes, it can be substituted by any atom or group of atoms with a weight of 1 to 200 Yes, where both are selected from: alcohols, organic acids, alkyl groups, amino groups, halogens, alkyl halides, alkyloxy groups and mercapto groups to be use alone or in combination with other compounds as medicaments stem for people and animals; excluding the compounds of Formula I, where it is H, substituted with OH, NH or CH, for the prevention and treatment of cardiovascular disease and obesity and for the treatment of cancer of the lungs, brain and prostate. 2. The compound of Formula I according to claim 1, where it is substituted by a group selected from: OH, NH and CH, substituted by H, for use in the prevention of cancer and / or the prophylaxis and / or treatment of skin pathologies, neurodegenerative pathologies, inflammation, infectious pathologies or metabolic pathologies, such as hypercholesterolemia, hypertriglyceridemia, diabetes or metabolic syndrome. 3. The compound of Formula I according to claim 1, where it is substituted by a group selected from: F, FC, HS and O-CH, substituted by H, for use in the prevention and / or treatment of cancer, vascular pathologies, obesity, skin pathologies, metabolic pathologies, neurodegenerative pathologies inflammation or infectious pathologies. 4. The compound of Formula I according to claim 1, wherein it is substituted with a group selected from: OH, NH, CH, F, FC, HS, O-CH, PO (CH-CH) or CHCOO, and may be substituted with sodium (Na), methyl ester (OMe), ethyl ester (EE) or ammonium (NH) for use1. Соединение Формулы I:-COO-CH-(CH)-CH=CH-(CH)-CH, его соли и его фармацевтически приемлемые производные, гдеимогут принимать любое значение от 0 до 14,может быть замещен любым а
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