GENETICALLY MODIFIED MULTI-SPECIFIC ANTIBODIES AND OTHER MULTIMERIC PROTEINS WITH ASYMMETRIC MUTATIONS IN THE CH2-CH3 REGION

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专利权人:

JANSSEN BIOTECH; INC.

发明人:

ADAM ZWOLAK,MARK CHIU

申请号：

BR112019025583

公开号：

BR112019025583A2

申请日:

2018.06.04

申请国别(地区):

BR

年份:

2020

代理人:

摘要：

the present invention relates to genetically modified multispecific antibodies and other multimeric proteins with asymmetric mutations in the ch2-ch3 region and to methods of producing and using them.a presente invenção se refere a anticorpos multiespecíficos geneticamente modificados e outras proteínas multiméricas com mutações assimétricas na região ch2-ch3 e a métodos para produzi-los e utilizá-los.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/