For the manufacture of an ophthalmic lens, the ophthalmic lens includes a gel matrix, at least one first polyelectrolyte coating layer, at least one second polyelectrolyte coating layer, and drugs. The first polyelectrolyte coating layer is formed on the gel matrix. The second polyelectrolyte coating layer is formed on the first polyelectrolyte coating layer. The drugs are in place between the first polyelectrolyte coating layer and the second polyelectrolyte coating layer. The first polyelectrolyte coating layer and the second polyelectrolyte coating layer interact electrostatically. When intraocular pressure (IOP) rises, the electrostatic interaction between the first polyelectrolyte coating layer and the second polyelectrolyte coating layer is broken and the drugs are released.一種眼用鏡片，包括一基體、形成在基體表面的第一聚電解質包覆層和第二聚電解質包覆層、以及形成在第一聚電解質包覆層及第二聚電解質包覆層之間的藥物，基體與第一聚電解質包覆層帶有的電荷的電性相反，第二聚電解質包覆層與第一聚電解質包覆層帶有的電荷的電性相反，第一聚電解質包覆層與基體之間及第一聚電解質包覆層與第二聚電解質包覆層通過電荷的相互吸引結合在一起並處在靜電平衡狀態，當眼內壓升高時，靜電平衡狀態被破壞，從而釋放位於第一聚電解質包覆層及第二聚電解質包覆層之間的藥物。
