Disclosed is a pharmaceutical composition which has little adverse side effects including abdominal pain and also has an excellent subcutaneous fat- or visceral fat-diminishing effect. The pharmaceutical composition comprises the following components (A) and (B): (A) at least one herbal medicine selected from the group consisting of divaricate saposhnikovia miraculous powder (fang-feng-tong-sheng-san) and major bupleurum decoction (da-chai-hu-tang)； and (B) at least one pantethine component selected from pantethine, a salt of pantethine, pantothenic acid, a salt of pantothenic acid, pantetheine and panthenol.
