Immediate and modified release oral dosage forms of tevipenem pivoxil comprising a dosage form core are provided. The dosage form core comprises tevipenem pivoxil in free base or salt form, a binder, a lubricant, an excipient, optionally with a diluent, and optionally additional excipients. The weight ratio of tevipenem pivoxil to excipient in the dosage form core is 30:60 to 60:30. The present disclosure includes methods of treating bacterial infections, including complex urinary tract infections.剤形コアを含むテビペネムピボキシルの即放性および調節放出性経口剤形が提供される。剤形コアは、遊離塩基または塩形態のテビペネムピボキシル、結合剤、潤滑剤、随意に希釈剤を含む賦形剤、および随意に追加的賦形剤を含む。剤形コア内のテビペネムピボキシル対賦形剤の重量比は、３０：６０～６０：３０である。本開示は、複雑な尿路感染症を含む細菌感染症を治療する方法を含む。
