There is described a bimodal pharmaceutical composition comprising effectiveamounts of a first active ingredient which substantially comprises a coarsefraction and a second active ingredient which substantially comprise a finefraction characterised in that the coarse fraction possesses a greater massmedian aerodynamic diameter (MMDA) than the fine fraction. There is alsodescribed a method of a method of delivering a therapeutically effectiveamount of a substantially fine active ingredient to the lung of a patient bythe co-administration with a substantially coarse active ingredient.
