Linda A. Pestano;Alan F. Wahl;Che-leung Law;Nathalie Scholler
发明人:
Che-leung Law,Alan F. Wahl,Nathalie Scholler,Linda A. Pestano
申请号:
US13491475
公开号:
US08609104B2
申请日:
2012.06.07
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are anti-CD70 antibodies and derivatives thereof conjugated to cytotoxic therapeutic agents, as well as pharmaceutical compositions and kits comprising the antibody- and antibody derivative-drug conjugates. Also disclosed are methods, for the treatment of a CD70-expressing cancer, comprising administering to a subject the disclosed pharmaceutical compositions.