Lianyungang Runzhong Pharmaceutical Co., Ltd.; Ltd.;Centaurus Biopharma Co., Ltd.;Chia Tai Tianqing Pharmaceutical Group Co.;Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Provided are a sultam compound having isocitrate dehydrogenase 1 (IDH1) inhibitory activity as represented by formula I or pharmaceutically-acceptable salts, solvates or hydrates thereof, a preparation method therefor, and a pharmaceutical composition containing the compound. The compound or the pharmaceutically-acceptable salts, solvates or hydrates thereof, and the pharmaceutical composition containing the compound can be used to treat IDH1 mutation-induced cancers.