Medicament (A) comprises 5-methyl-(6S)-tetrahydrofolate, one or more estrogen and/or gestagene, optionally vitamin B6 and/or vitamin B2 and auxiliary or carrier materials. Independent claims are included for: (1) a kit comprising at least 20 daily dose units of (A), at least a daily dose unit containing 5-methyl-(6S)-tetrahydrofolate and optionally vitamin B6 and/or vitamin B2 (where the amount of all the dose units in the kit is at least 28, and the dose unit of (A) is administrated first and subsequently the dose unit containing 5-methyl-(6S)-tetrahydrofolate)； and (2) preparation of the medicament which comprising granulating 5-methyl-(6S)-tetrahydrofolate. ACTIVITY : Cardiant； Uropathic； Cytostatic； Antiinfertility； Tests are described, but no results are given. MECHANISM OF ACTION : None given.
