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A composition for treating or preventing toxoplasmosis comprising Oleanolic acid
专利权人:
CHOI, WON HYUNG;최원형
发明人:
최원형,CHOI, WON HYUNGKR
申请号:
KR1020180060029
公开号:
KR1020190134958A
申请日:
2018.05.27
申请国别(地区):
KR
年份:
2019
代理人:
摘要:
Oleanolic acid (Oleanolic acid) in the present invention has not been reported to the anti-toxoplasmosis effect against toxoplasmosis or toxoplasmosis, which is one of the common infectious diseases. In the present invention, it has been confirmed that the test substance has an anti-toxoplasmosis effect or activity exhibiting survival inhibition or schizophage inhibition and growth inhibition effect on toxoplasmosis worms, and toxoplasmosis (Toxoplasmosis) It was confirmed that it can be used as a composition for the treatment, improvement or prevention of. The present invention is a pharmaceutical composition for the treatment, improvement or prevention of toxoplasmosis containing oleanolic acid as an active ingredient, a health food composition for prevention or improvement, a feed composition for prevention or improvement, a veterinary pharmaceutical composition for prevention, treatment or improvement and prevention Or it relates to a quasi-drug composition for improvement. The pharmaceutical composition, health food composition, feed composition, animal pharmaceutical composition, and quasi-drug composition according to the present invention have toxoplasmosis effect or activity by having anti-toxoplasmagenic effect or activity showing survival inhibition or cleavage growth inhibition and growth inhibition action against toxoplasma worms. It can be usefully used as a composition for the treatment, improvement or prevention of symptoms.본 발명에서 올레아놀릭산(Oleanolic acid)은 기존에는 인수공통전염병의 하나인 톡소포자충증 또는 톡소플라즈마증에 대한 항톡소포자충증 효과가 보고된바 없다. 본 발명에서는 상기 시험물질이 톡소포자충에 대한 생존저해작용 또는 분열증식 억제 및 성장저해작용을 나태내는 항톡소포자충 효과 또는 활성을 가지고 있음이 확인되었으며, 이를 활용한 톡소플라즈마증(톡소포자충증, Toxoplasmosis)의 치료, 개선 또는 예방을 위한 조성물로 사용될 수 있음을 확인하였다.본 발명은 올레아놀릭산을 유효성분으로 포함하는 톡소플라즈마증의 치료, 개선 또는 예방용 약학 조성물, 예방 또는 개선용 건강식품 조성물, 예방 또는 개선용 사료 조성물, 치료, 개선 또는 예방용 동물의약품 조성물 및 예방 또는 개선용 의약외품 조성물에 관한 것이다. 본 발명에 따른 약학 조성물, 건강식품 조성물, 사료 조성물, 동물의약품 조성물 및 의약외품 조성물은 톡소포자충에 대한 생존저해작용 또는 분열증식 억제 및 성장저해작용을 나태내는 항톡소포자충 효과 또는 활성을 가짐으로
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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