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Methods of Diagnosing and Treating Cancer in Patients Having or Developing Resistance to a First Cancer Therapy
专利权人:
Levi A. Garraway
发明人:
Levi A. Garraway,Cory M. Johannessen
申请号:
US15480126
公开号:
US20170268069A1
申请日:
2017.04.05
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A method of identifying a subject having cancer who is likely to benefit from treatment with a combination therapy with a RAF inhibitor and a second inhibitor is provided. A method of treating cancer in a subject in need thereof is also provided and includes administering to the subject an effective amount of a RAF inhibitor and an effective amount of a second inhibitor, wherein the second inhibitor is a MEK inhibitor, a CRAF inhibitor, a CrkL inhibitor or a TPL2/COT inhibitor. A method of identifying a kinase target that confers resistance to a first inhibitor is also provided.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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