Compounds, Compositions and Methods of Inhibiting Alpha-Synuclein Toxicity

• 收藏
• 分享

专利权人:

WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH

发明人:

LINDQUIST, SUSAN L

申请号：

NZ58477305

公开号：

NZ584773A

申请日:

2005.09.16

申请国别(地区):

NZ

年份:

2012

代理人:

摘要：

Disclosed is the use of a compound of Formula III e.g. 2,3,4,7,8,9-hexahydro-1H-cyclopenta[h]quinolin-2-one or a pharmaceutically acceptable derivative thereof as hereinbefore defined, for treating a disease involving a-synuclein toxicity and/or fibril formation, inhibiting or preventing a-synuclein fibril growth, and/or causing disassembly, disruption, and/or disaggregation of n-synuclein fibrils and a-synuclein-associated protein deposits e.g. Parkinsons disease.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/