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COMPOSITIONS ET PROCEDES UTILISANT UN INHIBITEUR EPIGENETIQUE
专利权人:
DANA-FARBER CANCER INSTITUTE; INC.
发明人:
WUCHERPFENNIG, KAI,TAY, RONG EN
申请号:
CA3047334
公开号:
CA3047334A1
申请日:
2018.01.09
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
Provided herein are novel methods for increasing T cell effector function in a T cell populations, as well as methods for increasing T cell effector function in a subject. The methods include contacting a T cell in a T cell population with a pharmaceutical composition comprising an antagonist of histone deacetylase 3 (HDAC3). Also provided herein are methods for identifying a compound that modulates HDAC3 activity in cytotoxic T cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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