Manganese complexes with substituted bisphosphonates useful as imaging and therapeutic agents

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专利权人:

Duke University

发明人:

Lascola, Christopher David

申请号：

AU2016403775

公开号：

AU2016403775A1

申请日:

2016.10.26

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Provided herein is a compound useful as a magnetic resonance imaging (MRI) contrast agent and a therapeutic agent, said compound having a structure represented by: Y – X – Z wherein, X is Mn(II), and Y and Z are each independently a bisphosphonate coupled to one or more therapeutic agents. Methods of use of the compound for MRI imaging and treatment for cancer or a microbial infection are also provided.

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中国工程科技知识中心

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