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PH-RESPONSIVE LIPOSOME
专利权人:
发明人:
申请号:
EP10750881.4
公开号:
EP2407158A1
申请日:
2010.03.10
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention provides pH-responsive liposomes which are capable of holding a desired substance in an acidic pH environment and releasing the desired substance in a basic pH environment.The present invention uses pH-responsive liposomes comprising, as constituent lipids thereof, a cationic amphiphilic molecule and at least one of an anionic amphiphilic molecule and a twitterionic amphiphilic molecule, wherein the liposomes, when dispersed in an aqueous medium, have a positive zeta potential in an acidic environment where the dispersion has a pH of less than 6.5 and have a negative zeta potential in a basic environment where the dispersion has a pH of 8.5 or more.
来源网站:
中国工程科技知识中心
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