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UTILISATION DU CD147 COMME RECEPTEUR POUR L'ADHESION IMPLIQUANT LES PILI DES MENINGOCOQUES A L'ENDOTHELIUM VASCULAIRE
专利权人:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;UNIVERSITE PARIS DESCARTES
发明人:
NASSIF, XAVIER,BOURDOULOUS, SANDRINE,JOIN-LAMBERT, OLIVIER
申请号:
CA2875391
公开号:
CA2875391A1
申请日:
2013.07.15
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention concerns the use of an inhibitor of an interaction between type IV pilus-associated protein and CD147 for preventing or treating meningoccal bacteraemia and/or infection. The present invention also relates to the combined use of such inhibitor and of an anti-bacterial compound, such as one used to prevent or treat a meningococcal infection. The invention also relates to a method for the prevention and/or treatment of meningococcal bacteraemia and/or infection, and to a method for screening inhibitors of the interaction between type IV pilus-associated protein and CD147.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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