PROCÉDÉ DE PRODUCTION DE FEUILLETS DE CELLULES SUPERPOSÉES, FEUILLETS DE CELLULES SUPERPOSÉES DOTÉS D'UN RÉSEAU VASCULAIRE OBTENU PAR CE PROCÉDÉ, ET PROCÉDÉ D'UTILISATION ASSOCIÉ
TOKYO WOMEN'S MEDICAL UNIVERSITY;TOKYO WOMENS MEDICAL UNIVERSITY
发明人:
SEKINE, HIDEKAZU,SHIMIZU, TATSUYA,OKANO, TERUO
申请号：
EP11825224
公开号：
EP2617810A4
申请日:
2011.09.14
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
A method for producing multilayered cell sheets, including producing a vascular bed which includes an artery-vein loop and in which a capillary vascular network is constructed； layering cell sheets on the vascular bed； and perfusing a culture medium in vitro to construct a vascular network in the cell sheets. The production method enables vascular networks to be constructed in cell sheets and enables thick multilayered cell sheets to be easily produced by layering the cell sheets. Such thick multilayered cell sheets are useful as in vivo tissue-like products for regenerative medicine for various tissues and for evaluation of drugs and the like.
