STAT3 signaling-related disorders, such as solid tumors, blood cancers, benign tumors, hyperproliferative diseases, inflammation, autoimmune diseases, graft or transplant rejection, delayed physiology of grafts or transplanted tissues, neurodegenerative diseases and viral infections Disclosed are sulfonamide analogs of gallieralactone of formula (I) as STAT3 inhibitors for use in the treatment of disease. Sulfonamides contain cyclic substituents. [Selection diagram] NoneＳＴＡＴ３シグナル伝達関連障害、例えば、固形癌、血液癌、良性腫瘍、過剰増殖疾患、炎症、自己免疫疾患、移植片又は移植拒絶、移植片又は移植組織の生理機能の遅延、神経変性疾患及びウイルス感染症の処置に使用されるＳＴＡＴ３阻害剤としての式（Ｉ）のガリエララクトンのスルホンアミド類似体を開示する。スルホンアミドは環状置換基を含む。【選択図】なし
