CHANG-YONG SHIN,JI-SU KIM,MIN-JUNG LEE,PUNNA REDDY ULLAPU,SUN-HO CHOI,WOO YOUNG KWAK
申请号:
BR112019003949
公开号:
BR112019003949A2
申请日:
2016.08.26
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
The present invention relates to an innovative (r) - (1-methylpyrrolidin-3-yl) methyl (3'-chloro-4'-fluoro- [1,1'-biphenyl] -2-yl) carbamate salt and a crystalline form thereof. In addition, the innovative (r) - (1-methylpyrrolidin-3-yl) methyl (3'-chloro-4'-fluoro- [1,1'-biphenyl] -2-yl) carbamate salt and the crystalline form of the themselves according to the examples of the present invention have remarkably excellent stability, hygroscopicity and solubility.a presente invenção refere-se a um sal de (r)-(1-metilpirrolidina-3-il)metil(3?-cloro-4?-fluoro-[1,1?-bifenil]-2-il)carbamato inovador e uma forma cristalina dos mesmos. além disso, o sal (r)-(1-metilpirrolidina-3-il)metil(3?-cloro-4?-fluoro-[1,1?-bifenil]-2-il)carbamato inovador e a forma cristalina dos mesmos de acordo com os exemplos da presente invenção têm estabilidade, higroscopicidade e solubilidade notavelmente excelentes.