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AMINOGUANIDINES AS MELANOCORTIN RECEPTOR LIGANDS USEFUL FOR THE TREATMENT OF INFLAMMATION AND AUTOIMMUNIE DISORDERS
专利权人:
ANAMAR AB
发明人:
LUNDSTEDT, TORBJORN,SEIFERT, ELISABETH,LEK, PER,BOMAN, ARNE
申请号:
NZ57754607
公开号:
NZ577546A
申请日:
2007.12.13
申请国别(地区):
NZ
年份:
2012
代理人:
摘要:
Disclosed are aminoguanidine compounds of formula (I), salts thereof, and methods for their preparation. Specific examples of compounds of formula (I) include: N-(2-Methylthio-3-chlorobenzylideneamino)guanidine hydrochloride, N-(2-Chloro-(3-ethoxycarbonyl)-benzylideneamino)guanidine trifiouroacetate, N-(2-Chloro-3,4-dimethylthiobenzylideneamino)guanidine, N-(2-MethyIthio-3-chlorophenylpropylideneamino)guanidine, N-(2-Chloro-4-Methoxy-3-methylthiophenylpropylideneamino)guanidine, and N-(2-Chloro-3-Methoxy-4-methylthiophenylpropylideneamino)guanidine. Compounds of formula (I) are useful for treating inflammation such as arthritic conditions and for inducing central nerve regeneration.
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