A probe may be inserted into a body cavity to perform diagnosticintervention(s), therapeutic intervention(s), or both.The probe may be inserted through a body aperture that is naturally occurringor man-made, intentionally or by accident. The bodyaperture may form a seal encircling the probe so that insufflation retentionmaterial may be effectively retained in the body cavity sothat an operator can perform the intervention(s). However, there may beleakage of the insufflation material. The insufflation retentiondevice is configured to form an effective seal contactingly adjacent the bodyaperture and to provide a passageway for the introductionof the probe into the body cavity, such that a diagnostic intervention ortherapeutic intervention or both may be performed.