A medical device is provided, configured to access a target site within a patient body. The device may be provided as a kit including pre-assembled components. Embodiments of the device include an elongate flexible access needle including a needle lumen disposed through at least a longitudinal length of the needle an elongate wire guide pre-loaded into at least a lengthwise portion of the needle lumen and extending to at least near a distal end of the needle end and a needle sheath including a longitudinal sheath lumen through which the access needle is disposed where the distal needle end comprises a piercing tip configured for penetrating tissue to access a target site. A method of use is provided where the needle may be withdrawn over the pre-loaded wire guide after it has been directed to a target site and the sheath as been advanced over the needles distal end, in a manner freeing the wire guide for further guidance or direction, and for introduction of another device along the wire guide.
