SINGLE NUCLEOTIDE POLYMORPHISM (SNP) TARGETING THERAPIES FOR THE TREATMENT OF HUNTINGTONS DISEASE

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专利权人:

Neil Aronin

发明人:

Neil Aronin,Edith Pfister,Phillip D. Zamore

申请号：

US13263961

公开号：

US20120136039A1

申请日:

2010.04.08

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The present invention relates to the discovery of (SNPs) significantly associated with Huntingtons disease (HD). The present invention utilizes RNA silencing technology (e.g. RNAi) against such SNPs optimally combined with select additional SNP targeting silencing agents, thereby resulting in an effective treatment of significantly-sized patient populations. Silencing agents having enhanced discriminatory properties are also featured.

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中国工程科技知识中心

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