A rehabilitation footwear comprises a shoe body, multiple fasteners, a lower back guard pad, an upper back guard pad, a lower front guard pad, an upper front guard pad, and two supporting frames. A full-cover rehabilitation footwear can be built up by combining the shoe body, the lower back guard pad, the upper back guard pad, the lower front guard pad, and the upper front guard pad together with the multiple fasteners. A supporting-type rehabilitation footwear can be built up by combining the shoe body, the lower back guard pad, the middle back guard pad, the lower front guard pad, and the middle front guard pad together with the multiple fasteners. A frame-type rehabilitation footwear can be built up by combining the shoe body and the two supporting frames together with the multiple fasteners. An adjustable rehabilitation footwear is provided.