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Guanidine compound
专利权人:
Astellas Pharma Inc.
发明人:
YOSHIHARA, Kousei,SUZUKI, Daisuke,YAMAKI, Susumu,YAMADA, Hiroyoshi,MIHARA, Hisashi,SEKI, Norio
申请号:
ES12758359
公开号:
ES2575478T3
申请日:
2012.03.13
申请国别(地区):
ES
年份:
2016
代理人:
摘要:
A compound represented by formula (I) or a salt thereof: ** Formula ** where A is ** Formula ** Q1 is N, Q2 is CRQ22, Q4 is CRQ42, Q5 is N, RQ22 and RQ42 are H, R1, R2, R3 and R4 are the same as or different from each other, and are H or halogen, E is a single bond, G is a single bond, J is a single bond, L is O or NH, U is a single bond or O, V is a single bond or C1-C6 alkylene that can be substituted with oxo (>; = O), W is a single bond, X is ** Formula ** where T1 is a single bond, CRT11RT12 or NRT13 , T2 is CRT21RT22 or NRT23, T3 is CRT31 or N, T4 is CRT41RT42 or NRT43, T5 is a single bond, (CRT51RT52) or NRT53, T6 is CRT61RT62,>; O or NRT63, RT11, RT12, RT13, RT21, RT22, RT23, RT31, RT41, RT42, RT43, RT51, RT52, RT53, RT61, RT62 and RT63 are the same as or different from each other, and are H, OH, halogen, C1-6 alkyl that can be substituted, aryl which a hetero ring group that can be substituted can be substituted, cycloalkyl which can be substituted rse, O- (C1-6 alkyl that can be substituted), NH (C1-6 alkyl that can be substituted), N (C1-6 alkyl that can be substituted) 2, NH (aryl that can be substituted), N (aryl that can be substituted substituted) 2, SO2- (C1-6 alkyl which can be substituted) or SO2- (cycloalkyl which can be substituted), or RT11 and RT61, RT11 and RT63, RT13 and RT61, RT13 and RT63, RT21 and RT31, RT23 and RT31, RT41 and RT51, RT43 and RT51, RT41 and RT53 or RT43 and RT53 can be combined with each other to form a new bond, or RT11 and RT12, RT21 and RT22, RT41 and RT42, RT51 and RT52 or RT61 and RT62 can be combined each with the other to form oxo (>; = O) and m is 1 or 2.Un compuesto representado por la fórmula (I) o una sal del mismo:**Fórmula** donde A es**Fórmula** Q1 es N, Q2 es CRQ22, Q4 es CRQ42, Q5 es N, RQ22 y RQ42 son H, R1, R2, R3 y R4 son los mismos que o diferentes cada uno del otro, y son H o halógeno, E es un enlace sencillo, G es un enlace sencillo, J es un enlace sencillo, L es O o NH, U es un enlace sencillo u
来源网站:
中国工程科技知识中心
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