PROBLEM TO BE SOLVED: To provide a regenerative medicine system with a cartilaginous tissue as a target, by which high regeneration effect can be expected.SOLUTION: The composition for regenerating a cartilaginous tissue includes an SDF-1 inhibitor as an active constituent. Further, the composition for regenerating a cartilaginous tissue is obtained by combining one or more cells selected from the group consisting of mesenchymal stem cells, chondroblasts, chondrocytes and dental pulp stem cells.【課題】高い再生効果が期待できる、軟骨組織を標的とした再生医療システムを提供することを課題とする。【解決手段】SDF-1阻害剤を有効成分とした軟骨組織再生用組成物が提供される。【選択図】なし