The present invention relates to the technical field of medical devices, in particular to an ultrasonic surgical integrated knife. The ultrasonic surgical integrated knife comprises: a handle (7), internally provided with an energy transducer； a cutter assembly, comprising a cutter bar (11) and a cutter head (12) which are sleeved with each other, wherein the cutter bar (11) and the cutter head (12) are detachably connected, and the cutter bar (11) is fixedly connected with the energy transducer. As to the ultrasonic surgical integrated knife provided in the present invention, the energy transducer is internally arranged in the handle, and the cutter bar (11) is fixedly connected with the energy transducer； the handle of the integrated knife produced in this way can be used for multiple times, while the disposable cutter head (12) in the cutter assembly can be replaced, and therefore, the risk of cross infection during surgery can be avoided； furthermore, the integrated knife does not need to be assembled before surgery, and such quickness for use brings great convenience to the surgery, thereby avoiding errors caused by tedious components during assembly.
