An injection device includes a housing, a receptacle for receiving a medicine cartridge and configured for attachment to a proximal end of the housing, and a leadscrew having an end for engaging with a bung of a cartridge. The leadscrew has a first thread extending axially along an outer surface thereof and at least one axially extending guide track. The injection device includes a rotatable drive mechanism for engaging with the first thread or guide track, and a guiding element for engaging with the other of the first thread or guide track, the guiding element being non-rotatable with respect to the housing during an injection operation, whereby rotation of the drive mechanism causes the leadscrew to move axially in a proximal direction in order to deliver a dose from the cartridge. The injection device further includes a stop member located proximal to the rotatable drive mechanism and the guiding element.
