Yu-Chen Tsai,Chi-Ying Huang,Ming-Hsi Chuang,Po-Cheng Lin,Chia-Hsin Lee
申请号：
US16710004
公开号：
US20200188465A1
申请日:
2019.12.11
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides a new method for decreasing level of a proinflammatory cytokine in a subject, which is further able to treating cytokine release syndrome caused by CAR T-cell therapy or a disorder mediated by an overproduction of a proinflammatory cytokine. The method comprises administering to the subject in need thereof a therapeutically effective amount of a pharmaceutical composition which is comprising at least one selected from the group consisting of Phenothiazine derivatives, Graptopetalum paraguayense extract, Rhodiola rosea extract and Histone Deacetylase (HDAC) inhibitors.
