PROBLEM TO BE SOLVED: To provide an indanol derivative which is an excellent neurokinin receptor antagonist.SOLUTION: This indanol derivative is a compound represented by general formula (I) [wherein R1 and R2 are each an optionally substituted (hetero)aryl R3 is -CO-R4, -CO-O-R4 or the like R4 is an alkyl, a cycloalkyl or the like A is CH2, CO or SO2 B is a single bond or the like D is O or CH2 E is an alkylene or an alkenylene and n is an integer of 1 to 3].COPYRIGHT: (C)2006,JPO&NCIPI【課題】優れたニューロキニン受容体拮抗剤を提供する。【解決手段】一般式(I)を有する化合物。【化1】[R1、R2:置換可(ヘテロ)アリール、 R3:-CO-R4、-CO-O-R4等、R4:アルキル、シクロアルキル等、 A:CH2、CO、SO2、 B:単結合等、D:酸素、CH2、 E:アルキレン、アルケニレン、 n:1-3]【選択図】なし
