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PARENTERAL FORMULATIONS OF PEPTIDES FOR THE TREATMENT OF SYSTEMATIC LUPUS ERYTHEMATOSUS
专利权人:
Sharon Cohen-Vered;Esmira Naftali;Vera Weinstein;Ety Klinger;Adrian Gilbert
发明人:
Sharon Cohen-Vered,Esmira Naftali,Vera Weinstein,Adrian Gilbert,Ety Klinger
申请号:
US13453979
公开号:
US20130023485A1
申请日:
2012.04.23
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The subject invention provides a pharmaceutical composition comprising: an aqueous carrier; from 0.1 mg/ml to 20 mg/ml of a pharmaceutically acceptable salt of a) a peptide comprising at least 12 and at most 30 consecutive amino acids, b) a peptide comprising consecutive amino acids having the sequence shown by any of SEQ ID NOS. 8-17, c) a peptide comprising consecutive amino acids having a sequence of any of a) and b), or at least two sequences in (a), or d) a peptide comprising consecutive amino acids having a sequence comprising at least two identical sequences included in (a); and a solubility enhancer; and wherein the composition has a pH between 4 and 9, and a method of alleviating symptoms of SLE in a human by administering an effective amount of the composition.
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