The present invention relates to a combination of an extract of the plant Salvia milttiorhiza and niacin and / or niacinamide and a cosmetic and / or nutraceutical composition comprising it. The invention further relates to the use of a combination of an extract of the plant Salvia miltiorrhiza and niacin and / or niacinamide to increase the deglycation of the proteins of the Extra-Cellular Matrix, in particular collagen, and / or to increase the expression of collagen to maintain and / or increase the firmness and / or elasticity of the skin and / or the mucous membranes and / or the scalp and / or to prevent and / or fight against skin aging and / or to maintain and / or increase the radiance of the complexion of the skin. The invention also relates to a cosmetic care method comprising the application, preferably topically, of a composition comprising the combination according to the invention. The invention finally relates to a combination of an extract of Salvia milttiorhiza and niacin and / or niacinamide in a dermatological composition for its use to fight against pathologies involving loss of firmness and / or elasticity of the skin and / or or mucous membranes and / or scalp and skin defects such as rosacea, telangiectasia, solar elastosis, disease cutix laxa and / or stretch marks. The invention furthermore relates to a dermatological composition comprising the combination according to the invention for increasing the healing of the skin and / or the mucous membranes and / or the scalp. La présente invention concerne une combinaison d'un extrait de la plante Salvia milttiorhiza et de niacine et/ou de niacinamide ainsi qu'une composition cosmétique et/ou nutraceutique la comprenant. L'invention concerne en outre l'utilisation d'une combinaison d'un extrait de la plante Salvia miltiorrhiza et de niacine et/ou de niacinamide pour augmenter la déglycation des protéines de la Matrice Extra-Cellulaire , notamment du collagène, et/ou augmenter l'expressio
