ARIZONA BOARD OF REGENTS on behalf of ARIZONA STATE UNIVERSITY;ZHANG, Peiming;LINDSAY, Stuart
发明人:
ZHANG, Peiming,LINDSAY, Stuart
申请号:
WO2017US53561
公开号:
WO2018064078(A1)
申请日:
2017.09.26
申请国别(地区):
世界知识产权组织国际局
年份:
2018
代理人:
摘要:
Apparatus and means by which a polysaccharide or other heterogeneous polymer is concatenated with a nucleic acid polymer that is captured by a primer on a polymerase tethered to a bead trapped by a nanopore. The translocation of the nanopore by the polysaccharide or other heterogeneous polymer is then controlled by the speed at which the polymerase releases newly synthesized nucleic acid or slows the motion of the nucleic acid as it is pulled on by an electrophoretic field.