SUBSTITUTED PYRROLIDINES AS FACTOR XIA INHIBITORS FOR THE TREATMENT THROMBOEMBOLIC DISEASES

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专利权人:

LTD.;ONO PHARMACEUTICAL CO.

发明人:

Akira IMAGAWA,Takashi KONDO,Taihei NISHIYAMA,Steve COURTNEY,Chris YARNOLD,Osamu ICHIHARA,Stuart FLANAGAN

申请号：

US15180382

公开号：

US20160287582A1

申请日:

2016.06.13

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the substituents are as defined in the description). The compounds of the general formula (I) are inhibitors of factor XIa, and are useful in the prevention of and/or therapy for thromboembolic diseases.

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中国工程科技知识中心

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