The present invention provides a kind of between of hair regeneration and uses, the treatment of mitigations of pain and the disease that are caused by the disease at joint portion the bones such as deformation arthropathy or rheumatoid arthritis, to the reparation of muscle of damage, the prevention of bedsore or treats useful stem cell filtrate preparation in turn. The characteristic of the stem cell filtrate preparation of one of present invention aspect is in what: the filtrate containing the stem cell for having removed cell membrane. The stem cell can be set as at least one kind of in leaf system stem cell, epithelial stem cell, pigmentosa stem cell, iPS cell and ES cell between the property of adipose tissue source, and then also may include fat cell or the effective component from cellular fat extraction.本發明提供一種對毛髮再生用、由變形關節病或類風濕性關節炎等骨間接合部之疾病引起之疼痛之緩和及該疾病之治療、進而對損傷之肌肉之修復、褥瘡之預防或治療有用之幹細胞濾液製劑。本發明之一態樣之幹細胞濾液製劑之特徵在於：含有已去除細胞膜之幹細胞之濾液。該幹細胞可設為選自脂肪組織源性間葉系幹細胞、上皮性幹細胞、色素性幹細胞、iPS細胞及ES細胞中之至少1種，進而亦可包含脂肪細胞或自細胞脂肪提取之有效成分。
