EVARTS, JERRY,PATEL, LEENA,KAPLAN, JOSHUA,TREIBERG, JENNIFER A.,PERREAULT, STEPHANE,PHILLIPS, GARY
申请号:
CA2895785
公开号:
CA2895785A1
申请日:
2013.12.20
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present disclosure provides phosphatidylinositol 3-kinase (PI3K) inhibitors of formula (J), or pharmaceutically acceptable salts thereof, in which n, m, R1, R2, and R3 are as defined herein. These compounds are useful for treatment of conditions mediated by one or more P13K isoforms, such as PI3K8. The present disclosure further provides pharmaceutical compositions that include a compound of formula (I), or pharmaceutically acceptable salts thereof, and methods of using these compounds and compositions to treat conditions mediated by one or more PI3K isoforms, such as PI3Kd.