Hassanein, Waleed,Fattah, Ihab,Lezberg, Paul,Khayal, Tamer,Havener, Robert,Abdelazim, Anas
申请号：
NZ74035312
公开号：
NZ740353A
申请日:
2012.04.13
申请国别(地区):
NZ
年份:
2019
代理人:
摘要：
Discloses a method of producing a solution for perfusing a lung at near physiologic conditions comprising the steps of: - adding pre-weighed amounts of dextran 40, sodium chloride, potassium chloride (KCL), magnesium sulfate anhydrate, disodium phosphate anydrate, monopotassium phosphate, glucose monohydrate, milrinone, nitroglycerin, antimicrobial agents and water to a container to form a solution； - mixing and heating the solution until fully dissolved； - monitoring the pH of the solution during mixing and adjusting the pH with 1M hydrochloric acid； - allowing the solution to cool； - filtering the solution； - dispensing the solution into a primary container； - sterilizing the filled primary container with heat using a sterilization cycle that has been validated to achieve a Sterility Assurance Level of 10^-6.
