The present teachings relate to compounds and compositions for treatment of cancers. In some embodiments, the composition comprises a platinum (IV) complex having at least one carboxylate or carbamate ligand.Linvention concerne des composés et des compositions de traitement de cancers. Dans certains modes de réalisation, la composition comprend un complexe de platine (IV) comportant au moins un ligand carboxylate ou carbamate.