Provided are a pharmaceutical composition for the prevention of hangover or elimination of hangover, and a food composition for eliminating hangover, which comprises the extract of longan meat as an active ingredient. [Selection diagram] Figure 1龍眼肉抽出物を有効性分として含むアルコール性二日酔い予防または二日酔い解消用薬学組成物および龍眼肉抽出物を含む二日酔い解消用食品組成物が提供される。【選択図】図1