Allan Bradley,Glenn Friedrich,E-Chiang Lee,Mark Strivens,Nicholas England
申请号：
US14052259
公开号：
US20140041067A1
申请日:
2013.10.11
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention relates to the provision of antibody therapeutics and prophylactics that are tailored specifically for human use. The present invention provides libraries, vertebrates and cells, such as transgenic mice or rats or transgenic mouse or rat cells. Furthermore, the invention relates to methods of using the vertebrates to isolate antibodies or nucleotide sequences encoding antibodies. Antibodies, heavy chains, polypeptides, nucleotide sequences, pharmaceutical compositions and uses are also provided by the invention.
