Non Aromatic substituted Heterocyclic Compounds; Pharmaceutical composition that includes a method for treating cancer; and selected glioma (glioblastoma), acute myelogenous leukemia, melanoma, non small cell lung cancer (NSCLC) cholangiocarcinomas and myelodysplastic syndromes (MDS), among others.
Provided are methods of treating a cancer characterized by the presence of a mutant allele of IDH1/2 comprising administering to a subject in need thereof a compound described here.<;p>;La presente invenció;n se refiere a un compuesto de fó;rmula I o una sal, tautó;mero, o hidrato farmacé;uticamente aceptable del mismo, composició;n carmaceutica que lo comprende, y uso ;del mismo en el tratamiento del cá;ncer.<;/p>;