PARK, DAE JONGKR,박대종,YOO, CHOONG LEOLKR,유충렬,KIM, DONG JINKR,김동진
申请号：
KR1020130046543
公开号：
KR1020140127996A
申请日:
2013.04.26
申请国别(地区):
KR
年份:
2014
代理人:
摘要：
In the present invention, provided are 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione, a novel polymorph J,K, and L of lenalidomide which is a pharmaceutical composition for reducing the concentration of a tumor necrosis factor a, and a manufacturing method thereof. The novel polymorphs of the present invention have greater physical and chemical properties such as thermal stability and water solubility than conventional polymorphs.COPYRIGHT KIPO 2015본 발명은 리날리도미드의 신규한 다형체 J, K, L 및 이들의 제조방법을 제공한다. 본 발명의 신규한 다형체들은 기존 다형체들보다 열안정성 및 용해도 등의 물리화학적 성질이 우수한 작용효과를 나타낸다.
