Shibnath Ghosal,Muruganandam Veeraragavan,Sanyasi R. Kalidindi
申请号:
US13669207
公开号:
US20130115316A1
申请日:
2012.11.05
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A group of indolealkylamino-withasteroid conjugates, isolated and purified from Withania somnifera, are described. A synthetic method of making an indolealkylamino-withasteroid compound is provided. In vitro acetyl cholinesterase inhibitory activity and methods for treatment of dementia and dementia-related disorders, such as Alzheimer's disease, and anxiety and depressive disorders in mammals are demonstrated with these novel compositions.