An automatically rotating, high-pressure sterilizer (10). A vessel (110) thereof has a vertical axis (151) that inclines to a horizontal rotation axis (150). A processing chamber (114) in the vessel (110) has a smooth and non-protruding inner surface (114a) or has a mechanical stirring element for stirring products (100). A corresponding processing method is also disclosed. The present automatically rotating, high-pressure sterilizer achieves high quality while having low operation costs, and is suited for high production volumes.