#$%^&*AU2013273788B220160616.pdf#####Cellular Extracts Abstract The present invention relates to the use of a composition comprising a salmon egg cellular extract comprising about 50 to 500 mg/ml fish egg protein, from about one to six grams/100 grams extract fish egg lipids, an osmolarity of from about 330 to 440 mOsm, and a pH of from about 5.0 to 7.7 to increase collagen protein production and/or collagen gene expression by the skin of a subject at the site of application. Likewise, the invention relates to a method of increasing collagen protein production and/or collagen gene expression by the skin of a subject, comprising: applying a composition comprising a fish egg cellular extract comprising about 50 to 500 mg/ml fish egg protein, from about one to six grams/ 100 grams extract fish egg lipids, an osmolality of from about 330 to 440 mOsm, and a pH of from about 5.0 to 7.7 to the skin of the subject under conditions such that collagen protein production and/or collagen gene expression is increased at the site of application.
