An arterial closure device includes an elongated catheter having a proximal end, an opposing flexible distal end, and a lumen extending between the proximal end and the distal end. An externalization needle and an internal catheter are disposed within the lumen. The externalization needle is in communication with a first plunger. A first threading needle and a second threading needle are positioned in separate threading channels and in communication with a second plunger. A suture has a first end attached to the second end of the first threading needle and a second end attached to the second end of the second threading needle. A primary aperture extends through a wall of the elongated catheter. A first threading aperture and a second threading aperture extend through the wall of the elongated catheter at opposing sides of the primary aperture.