Kugimiya, Akira,Tanino, Tetsuya,Sekiguchi, Mitsuaki,Mitsuoka, Yasunori,Kuroda, Norikazu,Nakamura, Jun
申请号：
AU2016332266
公开号：
AU2016332266A1
申请日:
2016.09.29
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The purpose of the present invention is to provide a double-stranded oligonucleotide comprising the CpG oligonucleotides mentioned below, as a nucleic acid derivative having an immunostimulatory activity.An adjuvant comprising a double-stranded oligonucleotide, wherein a first strand is a CpG oligonucleotide which is composed of 8 to 50 nucleotides, a second strand is an oligonucleotide which is composed of 8 to 60 nucleotides and contains a sequence capable of hybridizing with the first strand, and a lipid is bonded to the second strand through a linker or without a linker.
