A combination toothbrush and dental floss holder which allows at least one, and preferably two toothbrushes to be retained above a possibly contaminated surface. In alternate configurations, the toothbrush(es) may be retained in a vertical or horizontal orientation. The holder may even be positioned along the crimped end of a tube of toothpaste for greater distancing from the surface. An alternate embodiment uses a lid of a dental floss container to retain at least one toothbrush above a surface.