Herein described as liquid formulations of antibodies and biologically active fragments thereof that specifically bind to human ICOS polypeptide, exhibit increased in vivo ADCC activity and undergo reversible self-association in solution.ヒトICOSポリペプチドに特異的に結合し、増加したインビボADCC活性を示し、溶液中で可逆的な自己会合を起こす抗体およびその生物活性断片の液体製剤を、本明細書に記載する。【選択図】 図1